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Recent Publications

Focused Ultrasound Thermal Ablation and CD40 Agonism Reprograms Breast Tumor Immunity to Drive Regression and Memory

Zehra EF Demir, AeRyon Kim, Beyzanur G Ak, Micaiah SJ Lee, Thomas Sherlock, Stefanyda O Maslova, Andrew T Thede, Matthew R DeWitt, Melanie R Rutkowski, Natasha D Sheybani

bioRxiv

2026

Focused Ultrasound for Enhancing Cell-Based Immunotherapies in Neuro-Oncology

Tom Sherlock, Andrew Thede, Natasha Sheybani

Neuro-Oncology Advances

2026

Therapeutic Ultrasound for Multimodal Cancer Treatment: A Spotlight on Breast Cancer

Zehra E. Demir, Natasha D.Sheybani

Annual Review of Biomedical Engineering

2025

CAR-T Cell Therapy in Brain Malignancies: Obstacles in the Face of Cellular Trafficking and Persistence

Serge Yaacoub, Stefanyda Maslova, Elton VanNoy, Abigail Haffey, Khatereh Khorsandi, Natasha Sheybani, Dalia Haydar

Frontiers in Immunology

2025

How Sound Waves Could Revolutionize Cancer (Immuno)therapy

Natasha D. Sheybani

Acoustical Society of America

2024

MR Imaging-Guided Focused Ultrasound for Breast Tumors

Matthew DeWitt, Zehra E. Demir, Thomas Sherlock, David R. Brenin, Natasha D. Sheybani

Magnetic Resonance Imaging Clinics

2024

Intersections of Focused Ultrasound and Extracellular Vesicles: Toward Diversified Biomarker Enrichment and Discovery

Natasha D. Sheybani

The Journal of the Acoustical Society of America

2024

Barriers to immune cell infiltration in tumors

Marit M Melssen, Natasha D Sheybani, Katie M Leick, Craig L Slingluff Jr

Journal for ImmunoTherapy of Cancer

2023

Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound

E. Andrew Thim, Todd Fox, Tye Deering, Luke R. Vass, Natasha D. Sheybani, Mark Kester, Richard J. Price

Drug Deliv Transl Res

2023

An Adaptive and Interpretable Framework for Biomedical Image Analysis

Samarth Singh, Scott T Acton, Shayan Moosa, Natasha D Sheybani

IEEE

2023

Guidelines for Immunological Analyses Following Focused Ultrasound Treatment

Frederic Padilla, Jessica Foley, Kelsie Timbie, Timothy N. Bullock, Natasha D. Sheybani

Journal for ImmunoTherapy of Cancer

2023

Emerging applications of image-guided therapeutic ultrasound for brain tumor-directed immunomodulation and immunotherapy

Natasha D. Sheybani

The Journal of the Acoustical Society of America

2022

Profiling of the immune landscape in murine glioblastoma following blood brain/tumor barrier disruption with MR image-guided focused ultrasound

Natasha D Sheybani, Alexandra R Witter, William J Garrison, Wilson Miller, Timothy N J Bullock, Richard J Price

Journal of Neuro-Oncology

2021

ImmunoPET-informed sequence for focused ultrasound-targeted mCD47 blockade controls glioma

Natasha D. Sheybani, Victoria R. Breza, Soumen Paul, Katelyenn S. McCauley, Stuart S. Berr, G. Wilson Miller, Kiel D. Neumann, Richard J. Price

Journal of Controlled Release

2021

Focused Ultrasound Hyperthermia Augments Release of Glioma-derived Extracellular Vesicles with Differential Immunomodulatory Capacity

Natasha D. Sheybani, Alec J. Batts, Alexander S. Mathew, E. Andrew Thim, and Richard J. Price

Theranostics

2020

Combination of thermally ablative focused ultrasound with gemcitabine controls breast cancer via adaptive immunity

Natasha D Sheybani, Alexandra R Witter, Eric A Thim, Hideo Yagita, Timothy N J Bullock, Richard J Price

Journal for ImmunoTherapy of Cancer

2020

Perspectives on Recent Progress in Focused Ultrasound Immunotherapy

Natasha D. Sheybani and Richard J. Price

Theranostics

2019

Focused Ultrasound Immunotherapy for Central Nervous System Pathologies: Challenges and Opportunities

Colleen T. Curley, Natasha D. Sheybani, Timothy N. Bullock, and Richard J. Price

Theranostics

2017

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